Suzuki reactions are prone to catalyst poisoning. This means that it is wise to clean reaction equipment diligently and maintain a dedicated reactor for the Suzuki step. For very high value chemicals, Albemarle will run a reactor seasoning batch before starting the campaign.
A seasoning batch is typically the desired Suzuki reaction run at one-tenth the normal concentration. If the seasoning batch runs to ~90% completion, we generally consider the reactor seasoned.I've never heard of this, has anyone else? I'm not quite sure what they mean by "seasoned." This usually makes me think of "seasoning" a cast-iron pan, i.e. polymerizing a protective oil coating on the surface. In this case, I suspect that it is a test to see whether or not there are catalyst poisons (sulfur compounds, etc) on the reactor wall? It'd be interesting to know if there was a difference between different reactor materials (glass, stainless steel, Hastelloy.)